Romero was substituted in tears after picking up the season-ending injury in Sunday's 1-0 defeat at Sunderland.
Reports claiming that the Argentina international will return in time for the World Cup are believed not to be completely accurate, but Romero's season at club level is over.
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It is another monumental injury blow for new Spurs boss Roberto De Zerbi, who told reporters on Friday he had expected to rely on Mohammed Kudus only for the forward to suffer a fresh quad injury.
More to follow...
