Sciver-Brunt retired out on 48 in Southampton, with an ECB statement released later in the night saying that was a precautionary measure due to calf tightness.
The 33-year-old underwent a scan on Wednesday and after further assessment from the England medical team will now sit out Saturday's encounter with Scotland at Headingley as well as next Wednesday's meeting with West Indies at Lord's.
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Sciver-Brunt was sidelined from late April to earlier this month after suffering an injury to the same calf while playing for The Blaze in domestic cricket.
Off-spinner Charlie Dean will deputise as England captain in Sciver-Brunt's absence, just as she did for the ODI and T20I series against New Zealand and T20Is versus India earlier this summer.
England are two from two at the World Cup, with the four-wicket success against Ireland at the Utilita Bowl following an 87-run demolition of Sri Lanka at Edgbaston on opening night.
More to follow...
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