SandboxAQ brings its drug discovery models to Claude — no PhD in computing required

SandboxAQ brings its drug discovery models to Claude — no PhD in computing required Lucas Ropek 2:29 PM PDT · May 18, 2026 Drug discovery is one of the most expensive failures in modern industry. Finding a single viable molecule can take a decade and cost billions, and most candidates still don’t make it. A generation of AI startups has promised to fix that — most have made the problem less painful for researchers who are already technically sophisticated enough to use the tools. But SandboxAQ thinks the bottleneck isn’t the models. It’s the interface. The company has teamed up with Anthropic to integrate its scientific AI models directly into Claude — putting powerful drug discovery and materials science tools behind a conversational interface that requires no specialized computing infrastructure to use. Founded roughly five years ago as an Alphabet spinout, SandboxAQ counts Eric Schmidt, Google’s former CEO, as its chairman. The company, which has raised more than $950 million from investors, has built out a number of different business lines, including a cybersecurity business, for instance. One of the more unique things SandboxAQ does, however, is produce large quantitative models, or LQMs. These proprietary models are “physics-grounded,” meaning they’re built on the rules of the physical world rather than patterns in text. They can run quantum chemistry calculations and simulate both molecular dynamics and microkinetics, the study of how chemical reactions unfold at the molecular level. That matters because it tells researchers how candidate molecules are likely to behave before anyone sets foot in a lab. “Trained on real-world lab data and scientific equations, LQMs are AI models engineered for the quantitative economy, a $50+ trillion sector spanning biopharma, financial services, energy, and advanced materials,” the company said in a new release that strongly suggests Sandbox AQ isn’t building another chatbot or code assistant — it’s chasing the economy that AI is supposed to transform. Chai Discovery and Isomorphic Labs — both well-funded bets on better models — have focused on the science. SandboxAQ is focused on who can actually use it. “For the first time, we have a frontier [quantitative] model on a frontier LLM that someone can access in natural language,” Nadia Harhen, SandboxAQ’s general manager of AI simulation, told TechCrunch. Previously, users of SandboxAQ’s LQMs would have had to provide their own digital infrastructure to run the models. SandboxAQ’s customers tend to be computational scientists, research scientists, or experimentalists. Generally, these people work at large pharmaceutical or industrial companies and are searching for new materials that can become marketable products. “Our customers come to us because they’ve tried all the other software out there, and the complexity of their problem is such that it didn’t work or didn’t yield positive results for them when that translation went to take place in the real world,” said Harhen. When you purchase through links in our articles, we may earn a small commission. This doesn’t affect our editorial independence. Lucas Ropek Senior Writer, TechCrunch May 27 Athens, Greece StrictlyVC Athens is up next. Hear unfiltered insights straight from Europe’s tech leaders and connect with the people shaping what’s ahead. Lock in your spot before it’s gone. Most Popular Users turn to jailbreaking their older Kindles as Amazon ends support Lauren Forristal OpenAI launches ChatGPT for personal finance, will let you connect bank accounts Ivan Mehta US orders travelers on Air Force One to throw away gifts, pins, and burner phones after China trip Lorenzo Franceschi-Bicchierai OpenAI is reportedly preparing legal action against Apple; it wouldn’t be the first partner to feel burned Connie Loizos How to turn off Instagram’s new Instants feature and retract photos you accidentally shared Aisha Malik Spotify launches a Wrapped-style recap of your entire listening history Ivan Mehta Amazon launches 30-minute delivery across the US Sarah Perez X LinkedIn Facebook Instagram youTube Mastodon Threads Bluesky TechCrunchStaffContact UsAdvertiseCrunchboard JobsSite Map Terms of ServicePrivacy PolicyRSS Terms of UseCode of Conduct AnthropicSAPSamsungMarc LoreTechCrunch DisruptTech LayoffsChatGPT © 2026 TechCrunch Media LLC.