ICE renews hunt for El Chapo's last two fugitive sons with massive reward

"Two down and two to go" blared the new wanted poster targeting the two remaining fugitive sons of infamous Mexican cartel kingpin Joaquin "El Chapo" Guzman-Loera, who is serving life-plus-30-years in Colorado's federal supermax prison.

On Monday, ICE posted a new wanted poster for two members of "Los Chapitos" — Ivan Archivaldo Guzman Salazar and Jesus Alfredo Guzman Salazar, two of El Chapo's sons with his first wife, Alejandrina Maria Salazar-Hernandez.

After El Chapo's final capture in 2016, control of the powerful Sinaloa Cartel shifted to Ismael "El Mayo" Zambada. Following Zambada's arrest during the Biden administration, leadership passed to Guzman's four sons.

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Both the Trump administration in the U.S. and the Sheinbaum administration in Mexico have said they are focused on cracking down on cartel's new leadership.

"Two down and two to go with $10 million reward," the wanted poster read, with Xs over the faces of the already captured Joaquin Guzman Lopez and Ovidio Guzman Lopez.

The two captured Chapitos are reportedly cooperating with authorities and have not yet been sentenced, but Ivan and Jesus remain "armed and dangerous," according to ICE.

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The two fugitives are charged with conspiracy to distribute a controlled substance and operating a continuing criminal enterprise.

Two of Guzman's four sons have already been captured through Operation Take Back America, an initiative seeking the "total elimination of cartels and transnational criminal organizations" in order to protect U.S. communities from violent crime.

U.S. Attorney for the Northern District of Illinois Andrew Boutros said in a recent statement that efforts to capture El Chapo’s sons are the latest steps "in our efforts to bring to justice drug lords and other dangerous criminals who poison the American public with illegal and harmful drugs and who otherwise engage in violence and corruption to carry out their and their enterprises’ wide-reaching criminal activities."

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In his plea agreement, Guzman Lopez admitted that he and his cartel associates committed violence against law enforcement officials, rival drug traffickers and members of their own organization to protect the Sinaloa Cartel's trafficking operations.

Fox News Digital reached out to ICE and DHS for additional comment and information on the mission to capture the two at-large Chapitos.