Five key weight loss jab side effects reported by 43 percent of patients

Five key weight loss jab side effects reported by 43 percent of patientsA new study has highlighted the most common side effects of weight loss jabsCommentsNewsFiona Callingham Lifestyle writer13:20, 14 Apr 2026View 3 ImagesA new study has named some of the most common potential side effects of weight loss jabs(Image: Getty)A groundbreaking study has identified some of the most frequently reported side effects of weight loss injections. Research found that almost half of participants using GLP-1 inhibitors were experiencing problems.‌GLP-1 (glucagon-like peptide-1) is a naturally occurring gut hormone that regulates blood sugar levels and appetite. The use of GLP-1 inhibitors, or receptor agonists, has rocketed in popularity in recent years owing to their proven effectiveness in managing blood sugar levels in diabetic patients and supporting weight loss.‌Available in injectable form, some of these drugs can be prescribed through the NHS to eligible patients. However, as with all medications, health authorities have cautioned that they can trigger side effects.‌A new study has now drawn on anecdotal evidence from patients to pinpoint the most widespread side effects associated with the jabs. The research, published in Nature Health, used artificial intelligence to scrutinise social media posts, uncovering patient-reported side effects linked to these medicines that may not yet have been examined in clinical trials.View 3 ImagesAlmost half of participants using GLP-1 inhibitors reported side effects(Image: Getty)The study analysed more than 400,000 Reddit posts from nearly 70,000 users discussing GLP-1 receptor agonists, including semaglutide and tirzepatide. Among the most commonly reported side effects were gastrointestinal complaints, which are already flagged by health bodies such as the Medicines and Healthcare products Regulatory Agency (MHRA).‌The research also drew attention to reproductive symptoms, including irregular menstrual cycles and unexpected bleeding...